Posts Tagged ‘collagen’
Copper Tripeptide-1 has been shown to play a role in stimulating the production of collagen, aid in wound healing and tissue remodeling. It also has Antioxidant, Anti-Inflammatory, Anti Microbial and Anti-Tumor Effects.
What is Copper Tripeptide-1
Copper Tripeptide-1 is naturally occurring in the body, it is composed of the amino acids Glycyl-histidyl-lysine, which spontaneously binds to copper, also known as GHK-CU. Copper Tripeptide-1 has many benefits within the human body, however levels decrease with age. Given the benefits that it has for renewing, repairing and protecting the skin, it makes sense that this would be used in cosmeceutical skin care products.
Copper Tripeptide-1 is used topically for anti-aging and firming of the skin. As we age our skin becomes progressively thinner, this is due in part to the declining production of collagen in the dermis and keratinocytes in the epidermis. As we age the skins ability to protect and repair itself also declines and this contributes to the degradation or breakdown of collagen. Copper Tripeptide-1 plays a role in stimulating collagen production and in the proliferation of keratinocytes. This is very promising for anti-aging skin care
Wound Healing and Tissue Remodeling
Copper Tripeptide-1 is seen to play a role in accelerating wound healing and improved tissue remodeling. Studies done on diabetic wounds, showed that wounds healed up to three times faster and had a lower incidence of infection, in the presence of Copper Tripeptide-1. This is relevant to anti-aging, because as we age the levels of GHK-CU decrease, which can affect the ability for skin to repair and renew it’s self. Further more, many of the treatments used to improve skin appearance, take advantage of the skins wound healing ability to increase the production of collagen, elastin and hyaluronic acid. The more effective the skins wound healing ability is, the more effective the treatment may be.
Anti-Tumor and Protective Ability
Radiation from sun exposure and cancer treatments have damaging effects on DNA and induce aging. Copper Tri-petide-1 (GHK-CU) helps to protect DNA from these damaging effects. Tumor cell lines died in the presence of Copper Tri-peptide, however healthy cell lines were protected. Skin fibroblasts, are “master cells” responsible for producing collagen, elastin and hyaluronic acid. Fibroblast exposed to radiation have been shown to restore their function when in the presence of (GHK-CU).
Antioxidant, Anti-Inflammatory and Anti-Microbial Effects
Intrinsic antioxidants, are antioxidants that the body makes, they can not be obtained with diet. With age, the production of these intrinsic antioxidants declines. Some of these intrinsic antioxidants are induced by Copper Tripeptide-1. It also has anti-inflammatory and anti-microbial effects during wound healing and tissue remodeling stages.
Skin Care Products with Copper Tripeptide-1
Topical products with Copper Tripeptide-1 may be useful for post procedure skin care to enhance results. They definitely look to be a promising as part of an anti-aging skin care regimen, especially when used with other power house products such as retinoids, anti-oxidants and most importantly broad spectrum sun protection.
Innovative Skin Care has added Copper Tripeptide-1 to many of their iS Clinical line of skin care products, including the most recent “Youth Serum” which is quickly becoming an A-list favorite. It is also found in Super Serum Advance +, Reparative Moisture Emulsion, Youth Intensive Cream, Youth Complex and Youth Eye Complex.
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A serum that claims to give you the “best of both worlds”, how perfect is that?! Youth Serum is designed to provide an instant smoothing and tightening effect, and long term wrinkle reduction (via collagen production). Could this Youth Serum be the fountain of youth we are all searching for?
I think expecting any single skin care product to be “THE” fountain of youth, may just be setting you up for disappointment. I believe that the fountain of youth is a full comprehensive approach to anti-aging, which would include skin care products along with aesthetic treatments, healthy lifestyle, diet, excersise and what ever fits your personal beliefs towards a healthy mind and spirit. With that said, I think it is fair to say that Youth Serum is one of those things that will add to our fountain youth.
This serum is appropriate for all skin types, espesially when anti-aging is a concern. As someone who works in medical esthetics, I am very interested in the role this product plays in wound healing, tissue remodeling as well as it’s anti-tumor effect and ability to protect DNA from the damaging effects of radiation. I think this product would be very beneficial for those with thin or impaired skin that may have reduced wound healing ability due to medical conditions or treatments.
This serum uses intelligent proteins that target damaged sites, strengthen dermal structure, to smooth fine lines and firm skin. YOUTH SERUM’s safe, bio-identical growth factors gradually rebuild lost collagen to reduce fine lines and wrinkles long-term. The patented Extremozyme® technology, combined with a powerful blend of antioxidants, including vitamins A, C, E, and centella asiatica, encourage cellular health, provide UV photoprotection, and prevent environmental damage. The result is a more youthful, vibrant, and resilient complexion.
• Clinically proven to increase collagen synthesis
• Contains safe growth factors that shield skin from cancer development, improve skin firmness and elasticity
• Helps prevent DNA damage (Extremozyme technology)
• Excellent for use under makeup
Copper Tripeptide-1 Growth Factor – Copper Tripeptide-1 sequence is found naturally in your bodies collagen, and it stimulates the synthesis of new collagen. This is a bioidentical growth factor, which means that your body recognizes it and it can be put to use immediately. This growth factor has been shown to prevent tumors, helping to protect skin from cancer development. It stimulates collagen production, which restores the skin’s structure and smoothes wrinkles over time.
Extremozymes – Think of them like “extreme” enzymes, these enzymes are harvested organisms that are able to withstand extreme conditions.These enzymes work to nuture skin and prevent free radical damage with powerful antioxidants. Clinically proven to repair and protect fragile proteins and DNA components.
Intelligent Peptides & Proteins – Primarily pseudoaltermonas ferment extract, which is a glycoprotien from the Antarctic Sea. Clinically proven to adhear to damaged sites, providing targeted regeneration.
Active Algae Extracts – A potent intertidal seaweed extract, that is a rich source of a rare amino acid found only in collagen – which triggers the epidermis to repair collagen loss.
Asiaticoside, Asiatic Acid, & Madecassic Acid Sourced from Centella Asiatica – Efficacious antioxidants that stimulate collagen synthesis and improve microcirculation, capillary flow and vascular tone, to promote wound healing and reduction of scar tissue.
Vitamin A, C & E Blend – Powerful vitamin antioxidant blend.
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Ultherapy has become a popular anti-aging treatment for those looking to tighten, lift and avoid the thin skin associated with aging. The common question with any aesthetic treatment is “how long the effects will last” and with Ultherapy, the answer is a long time.
How Does Ultherapy Work?
Ultherapy is the only device that is cleared for skin tightening and lifting. It uses focused ultrasound to precisely target and treat tissue at three levels, the Superficial Dermis, Deep Dermis and most importantly the SMAS which is at the top of the muscle, all while leaving the surrounding tissue intact. We are not able to treat all these areas with chemical peels, micro-needling or even other devices such as lasers or Radio Frequency. So basically…. this is as good as it gets with the exception of surgery.
As we age the processes within the skin begin to slow, our skins fibroblast are more sluggish and we produce less hylauronic acid, elastin fibers become weak, we produce less collagen and our collagen becomes un-organized. This all results in lax skin that is less firm and thinning.
Many of the treatments we use in aesthetics, benefit from the skins wound healing ability. By creating a wound healing response in the skin we stimulate the fibroblast to produce more collagen. The type and length of the wound healing benefits can vary, depending on how and where the “wound” was created. For example a scratch or something like microdermabrasion may only be 14 days of increased collagen production, an IPL / BBL treatment is about 3 weeks, and RF treatments around 6 months. Ultherapy leads to an inflammatory wound healing response which stimulates long-term tissue remodeling and leads to further lifting and tightening. Increases collagen production is seen in skin biopsies 12 months after treatment.
Clinical tightening and lifting can be seen as early as 3-6 weeks,but the most appreciable results are seen at 3 months. The duration of response after a single treatment can be up to 2 years.
Anti-Aging Benefits of Ultherapy Observed in Study
– Increased dermal collagen by over 23.7%, new collagen is organized
– Increased over all dermal thickness
– Increased New collagen Type I (21%-30%) and collagen Type III (48%-68%)
– Increased amount of elastin, elastin fibers are more parallel and straighter
Repeating Ultherapy Treatments
The aging process is continues and regardless of which procedure you choose, maintenance is always necessary. The exact longevity of results with any treatment depends on your body’s ability to produce, maintain and breakdown collagen. The frequency of treatments will depend on age, health, lifestyle, condition of skin, other anti-aging measures taken and desired results. Although one year between treatments is most common, many opt for a second treatment as early as 6 months to boost results.Those who are younger may go as long as 2-3 years between treatments. Ultherapy works best as part of a comprehensive approach to aging, your skin care professional can work to customize a plan for your specific needs.
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The eyes are the focal pointe of the face and one of the first places we start to age. A professional chemical peel to treat the skin around the eyes, may be just what the doctor ordered.
A Medium Depth Peel will..
– Treat skin laxity, fine lines, “stretchable” wrinkles and scars.
– Improve skin texture, reducing roughness
– Treat hyper-pigmentation Brown spots and Melasma
– Tighten large pores
– Increase collagen and skin density
The skin around the eyes is thin and with age begins to show fine lines and take on a crepey texture. Treating the delicate skin around the eye can be tricky. Lasers can damage the eye, so this limits how we treat this area. Laser resurfacing can be done, if special laser eye shields are placed inside the eye. Chemical peels are another option for treating the skin around the eye, and when done by a skilled professional can be done up to the lash line.
Chemical peels that penetrate to the appropriate depth in the skin, can improve texture and tighten skin. A TCA peel that penetrates beyond the papillary dermis, just to the Immediate Reticular Dermis (IRD) will provide skin tightening effect, this is called a Medium Depth Peel. I am choosing not to mention the strength of TCA used, because I read too many horror stories online about people who attempted to do a professional peel at home. Skin care professionals are trained on how to determine where we are working in the skin, this is a medical grade peel and should be done by an experienced professional.
Aging Skin and Chemical Peel Intervention
Skin care professionals often talk about “skin cell turn over”. Skin cell turnover is the process of a new skin cell being produced, working it’s way up to the surface and replacing old skin cells which have been sloughed away. In young healthy skin this process takes about 6 weeks, however aging and sun damage slow this process. Chemical peels increase skin cell turnover, which in turn improves skin texture.
The production of growth factors, collagen, elastin and hylaraunic acid all slow with age, so the goal in anti-aging is to preserve and increase the production all of these things. Collagen is a protein that gives skin it’s volume strength and structure, while elastin is what gives skin it’s elasticity or ability to snap back. Hyaluronic acid is a key molecule involved in skin moisture, as it binds and retains water. Hyaluronic acid is also needed to bind collagen to elastin. When we do chemical peels and laser treatments that penetrate beyond the skins epidermis, we are benefitting from the skins own wound healing ability to up regulate growth factors and stimulate the production of collagen, elastin and hyluranic acid. The result is a thicker dermis, smoother surface and skin tightening.
What to expect
The day of the peel is considered day 1. On days 1 and 2 your skin looks okay, but it may look dry and slightly older. By day 3 skin begins to look dark or bronze, this will vary depending on your natural skin color, skin discolorations and depth of peel. Skin usually begins to peel on day 4 and is usually done by day 5. After the skin has peeled of it may be pink for a couple days. The healing process does vary for each person. Healthy skin will always recover more quickly with less inflammation.
During the peeling process you will need to follow the post peel instructions given to you by your skin care professional. This usually includes using a gentle cleanser, a hydrocortisone cream and mild moisturizer. An occlusive ointment such as Vasoline or Aquaphor may be recommended. It is VERY important to not pick or pull off the skin, let it peel in its own time! (seriously… don’t do it) You should also avoid sweating during the pealing phase, because it will create sweat beads under the skin that will cause it to peel of prematurely and thats bad. The skin should be protected with a totally physical sunscreen, I like Physical Eye UV Defense SPF 50 by Skin Ceuticals.
After the old skin has peeled off, it instantly looks and feels smother. The collagen production will continue to increase and the skin will continue to feel tighter. To keep the skin renewal process un regulated and functioning more similar to young skin, I usually recommend having around 4 TCA chemical peels around the eye area per year. Treatments should be scheduled over 6 weeks apart.
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